mHP.c {sp23design} | R Documentation |
Compute the modified Haybittle-Peto boundary for the final look
Description
Compute the modified Haybittle-Peto boundary for the final look
Usage
mHP.c(mu = c(0, 0, 0), v = c(1, 2, 3), b = 3, alpha = 0.05,
eps = 1/2, side = c("one", "two"))
Arguments
mu |
the mean vector |
v |
The variance vector, usually proportional to information in calendar time |
b |
The (constant) modified Haybittle-Peto boundary, typically computed
by |
alpha |
The significance level desired |
eps |
The fraction of alpha to use |
side |
one-sided or two-sided ( |
Details
Compute the modified Haybittle-Peto boundary for the final look
Value
the modified Haybittle-Peto boundary for the final look
Author(s)
Mei-Chiung Shih, Balasubramanian Narasimhan, Pei He
References
Lai, Tze Leung and Lavori, Philip W. and Shih, Mei-Chiung. Sequential Design of Phase II-III Cancer Trials, Statistics in Medicine, Volume 31, issue 18, p.1944-1960, 2012.
[Package sp23design version 0.9-1 Index]