sdac {simplexreg}

Data on Autologous Peripheral Blood Stem Cell Transplants in Alberta Health Service

Description

Autologous peripheral blood stem cell (PBSC) transplants have been widely used for rapid hematologic recovery following myeloablative therapy for various malignant hematological disorders. A study enrolled 242 patients who consented to autologous PBSC transplant after myeloablative doses of chemotherapy between year 2003 and 2008 at the Edmonton Hematopoietic Stem Cell Lab in Cross Cancer Institute - Alberta Health Services. The Data is a data frame containing information about the patients' age, gender, as well as their clinical characteristics.

Usage

data("sdac")

Format

A data frame with 239 observations on the following 5 variables.

age

patients' ages

gender

patients' genders

rcd

recovery rates for viable CD34+ cells

chemo

dummy variable indicating if a patient receives a chemotherapy on a one-day protocol(0) or on a 3-day protocol(1)

ageadj

adjusted age variable. age < 40 is set as the baseline age and other ages are adjusted by subtracting by 40

References

Allan, D. and Keeney, M. and Howson-Jan, K. and Popma, J. and Weir, K. and Bhatia, M. and Sutherland, D. and Chin_yee, I. (2002) Number of Viable CD34+ Cells Reinfused Predicts Engraftment in Autologous Hematopoietic Stem Cell Transplantation. BONE MARROW TRANSPL, 20: 967-72

Yang, H. and Acker, J. and Cabuhat, M. and Letcher, B. and Larratt, L. and McGann, L. (2005) Association of Post_Thaw viable CD34+ Cells and CFU-GM with Time to Hematopoietic Engraftment. BONE MARROW TRANSPL, 35: 881-887

Zhang, P. and Qiu, Z. and Shi, C. (2016) simplexreg: An R Package for Regression Analysis of Proportional Data Using the Simplex Distribution. Journal of Statistical Software, 71: 1–21