MUTATION_SCHEMES {shazam}

Amino acid mutation definitions

Description

Definitions of replacement (R) and silent (S) mutations for different amino acid physicochemical classes.

Format

A MutationDefinition object defining:

• CHARGE_MUTATIONS: Amino acid mutations are defined by changes in side chain charge class.

• HYDROPATHY_MUTATIONS: Amino acid mutations are defined by changes in side chain hydrophobicity class.

• POLARITY_MUTATIONS: Amino acid mutations are defined by changes in side chain polarity class.

• VOLUME_MUTATIONS: Amino acid mutations are defined by changes in side chain volume class.

References

1. https://www.imgt.org/IMGTeducation/Aide-memoire/_UK/aminoacids/IMGTclasses.html