| scale_variance {scITD} | R Documentation |
Scale variance across donors for each gene within each cell type. Generally, this should be done through calling the form_tensor() wrapper function.
Description
Scale variance across donors for each gene within each cell type. Generally, this should be done through calling the form_tensor() wrapper function.
Usage
scale_variance(container, var_scale_power)
Arguments
container |
environment Project container that stores sub-containers for each cell type as well as results and plots from all analyses |
var_scale_power |
numeric Exponent of normalized variance that is used for variance scaling. Variance for each gene is initially set to unit variance across donors (for a given cell type). Variance for each gene is then scaled by multiplying the unit scaled values by each gene's normalized variance (where the effect of the mean-variance dependence is taken into account) to the exponent specified here. If NULL, uses var_scale_power from container$experiment_params. |
Value
The project container with the variance altered for each gene within the pseudobulked matrices for each cell type.