bcwest {rvalues}

Breast Cancer Gene Expression Data

Description

Effect size estimates and standard errors obtained from gene expression measurements on 7129 genes across 49 samples.

Usage

data(bcwest)

Format

A data frame with 7129 observations on the following 2 variables.

estimates

a vector of effect size estimates

std.err

standard errors associated with effect size estimates

Details

A description of the original data may be found in West et al. (2001). For each gene, the effect size estimate was computed from the difference in the mean expression levels of the two groups (i.e., mean(bc-positive group) - mean(bc-negative group)).

Source

T. Hothorn, P. Buehlmann, T. Kneib, M. Schmid, and B. Hofner (2013). mboost: Model-Based Boosting, R package version 2.2-3, http://CRAN.R-project.org/package=mboost.

References

Mike West, Carrie Blanchette, Holly Dressman, Erich Huang, Seiichi Ishida, Rainer Spang, Harry Zuzan, John A. Olson Jr., Jeffrey R. Marks and Joseph R. Nevins (2001), Predicting the clinical status of human breast cancer by using gene expression profiles, Proceedings of the National Academy of Sciences, 98, 11462-11467.