rba_reactome_orthology {rbioapi} | R Documentation |
Get Orthologous (Computationally Inferred) Events
Description
Reactome incorporate manually curated human reactions and PANTHER's protein homology data to Computationally infer events in other eukaryotic species.
Usage
rba_reactome_orthology(event_ids, species_dbid, ...)
Arguments
event_ids |
Human Reactome event ID(s) to retrieve their orthologous events. |
species_dbid |
Reactome database ID (DbId) of the target species. (e.g
Mus musculus is 48892). See
|
... |
rbioapi option(s). See |
Details
In version 73 (11 June 2020), using an orthology-based approach,
Homo sapiens events was projected to 18,654 orthologous pathways (with
81,835 orthologous proteins) in 15 non-human species.
See
Reactome Computationally Inferred Events for more information.
Value
List containing found Orthologous event(s) in your supplied species and their pertinent information.
Corresponding API Resources
"POST https://reactome.org/ContentService/data/orthologies/ids/ species/{speciesId}"
References
Marc Gillespie, Bijay Jassal, Ralf Stephan, Marija Milacic, Karen Rothfels, Andrea Senff-Ribeiro, Johannes Griss, Cristoffer Sevilla, Lisa Matthews, Chuqiao Gong, Chuan Deng, Thawfeek Varusai, Eliot Ragueneau, Yusra Haider, Bruce May, Veronica Shamovsky, Joel Weiser, Timothy Brunson, Nasim Sanati, Liam Beckman, Xiang Shao, Antonio Fabregat, Konstantinos Sidiropoulos, Julieth Murillo, Guilherme Viteri, Justin Cook, Solomon Shorser, Gary Bader, Emek Demir, Chris Sander, Robin Haw, Guanming Wu, Lincoln Stein, Henning Hermjakob, Peter D’Eustachio, The reactome pathway knowledgebase 2022, Nucleic Acids Research, 2021;, kab1028, https://doi.org/10.1093/nar/gkab1028
Griss J, Viteri G, Sidiropoulos K, Nguyen V, Fabregat A, Hermjakob H. ReactomeGSA - Efficient Multi-Omics Comparative Pathway Analysis. Mol Cell Proteomics. 2020 Sep 9. doi: 10.1074/mcp. PubMed PMID: 32907876.
See Also
Examples
rba_reactome_orthology(event_ids = c("R-HSA-6799198", " R-HSA-72764"),
species_dbid = 49633)