rapamycin_dose_response {protti}

Rapamycin dose response example data

Description

Rapamycin example data used for the vignette about dose response data. The data was obtained from Piazza 2020 and corresponds to experiment 18. FKBP1A the rapamycin binding protein and 39 other randomly sampled proteins were used for this example dataset. The concentration range includes the following points: 0 (DMSO control), 10 pM, 100 pM, 1 nM, 10 nM, 100 nM, 1 uM, 10 uM and 100 uM.

Usage

rapamycin_dose_response

Format

A data frame containing peptide level data from a Spectronaut report.

Source

Piazza, I., Beaton, N., Bruderer, R. et al. A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes. Nat Commun 11, 4200 (2020). https://doi.org/10.1038/s41467-020-18071-x