binding2to1 {pbm}

Generate a 2:1 Binding Curve

Description

Returns a response value for given parameters at time, t.

Usage

binding2to1(
  t,
  t0,
  conc,
  kon1,
  koff1,
  rmax1,
  kon2,
  koff2,
  rmax2,
  drift = 0,
  offset = 0,
  doffset = 0
)

Arguments

t

Time.

t0

Time of dissociation.

conc

Analyte concentration.

kon1

Kon binding constant for first component.

koff1

Koff binding constant for first component.

rmax1

Maximum response, Rmax, for first component.

kon2

Kon binding constant for second component.

koff2

Koff binding constant for second component.

rmax2

Maximum response, Rmax, for second component.

drift

Optional. Parameter to add a linear baseline drift.

offset

Optional. Applies a global offset to the response value.

doffset

Optional. Applies an offset at the start of dissociation.

Examples

time <- seq(1,2000)
curve <- binding2to1(time,1000,900e-9,10000,0.01,0.4,2000,0.0003,0.5)
plot(curve)