crohn {opticskxi}

Crohn's disease data

Description

The data set consist of 103 common (>5% minor allele frequency) SNPs genotyped in 129 trios from an European-derived population. These SNPs are in a 500-kb region on human chromosome 5q31 implicated as containing a genetic risk factor for Crohn disease.

Imported from the gap R package.

An example use of the data is with the following paper, Kelly M. Burkett, Celia M. T. Greenwood, BradMcNeney, Jinko Graham. Gene genealogies for genetic association mapping, with application to Crohn's disease. Fron Genet 2013, 4(260) doi: 10.3389/fgene.2013.00260

Usage

data(crohn)

Format

A data frame containing 387 rows and 212 columns

Source

MJ Daly, JD Rioux, SF Schaffner, TJ Hudson, ES Lander (2001) High-resolution haplotype structure in the human genome Nature Genetics 29:229-232