| fish_oil_18 {openintro} | R Documentation | 
Findings on n-3 Fatty Acid Supplement Health Benefits
Description
The results summarize each of the health outcomes for an experiment where 12,933 subjects received a 1g fish oil supplement daily and 12,938 received a placebo daily. The experiment's duration was 5-years.
Usage
fish_oil_18
Format
The format is a list of 24 matrices. Each matrix is a 2x2 table, and below are the named items in the list, which also represent the outcomes.
- major_cardio_event
- Major cardiovascular event. (Primary end point.) 
- cardio_event_expanded
- Cardiovascular event in expanded composite endpoint. 
- myocardioal_infarction
- Total myocardial infarction. (Heart attack.) 
- stroke
- Total stroke. 
- cardio_death
- Death from cardiovascular causes. 
- PCI
- Percutaneous coronary intervention. 
- CABG
- Coronary artery bypass graft. 
- total_coronary_heart_disease
- Total coronary heart disease. 
- ischemic_stroke
- Ischemic stroke. 
- hemorrhagic_stroke
- Hemorrhagic stroke. 
- chd_death
- Death from coronary heart disease. 
- myocardial_infarction_death
- Death from myocardial infraction. 
- stroke_death
- Death from stroke. 
- invasive_cancer
- Invasive cancer of any type. (Primary end point.) 
- breast_cancer
- Breast cancer. 
- prostate_cancer
- Prostate cancer. 
- colorectal_cancer
- Colorectal cancer. 
- cancer_death
- Death from cancer. 
- death
- Death from any cause. 
- major_cardio_event_after_2y
- Major cardiovascular event, excluding the first 2 years of follow-up. 
- myocardial_infarction_after_2y
- Total myocardial infarction, excluding the first 2 years of follow-up. 
- invasive_cancer_after_2y
- Invasive cancer of any type, excluding the first 2 years of follow-up. 
- cancer_death_after_2y
- Death from cancer, excluding the first 2 years of follow-up. 
- death_after_2y
- Death from any cause, excluding the first 2 years of follow-up. 
Source
Manson JE, et al. 2018. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer. NEJMoa1811403. doi:10.1056/NEJMoa1811403.
Examples
names(fish_oil_18)
(tab <- fish_oil_18[["major_cardio_event"]])
chisq.test(tab)
fisher.test(tab)
(tab <- fish_oil_18[["myocardioal_infarction"]])
chisq.test(tab)
fisher.test(tab)