ondisc {ondisc}

ondisc: A package for out-of-memory computing on single-cell data

Description

Single-cell datasets are large and are growing in size as sequencing costs drop. The ondisc package is designed to facilitate large-scale computing on single-cell expression data by providing access to expression matrices out-of-memory. ondisc is functional (i.e., all objects are persistent) and efficient (i.e., all algorithms are theoretically optimal in time).