oceCens {oceCens}

oceCens: A package for ordered composite endpoints with censoring.

Description

An ordered composite endpoint combines several time-to-event endpoints into one score. The package compares two groups with two parameters, the win ratio, P[Y1>Y0]/P[Y0>Y1], and the Mann-Whitney parameter, P[Y1>Y0]+(1/2)P[Y1=Y0], where Y1 and Y0 are the oce scores in the two groups. The main function is oceTest, which calls many of the other functions and has several different methods for estimation. Statistical details are in Follmann, et al 2020.

References

Follmann, D., Fay, M. P., Hamasaki, T., and Evans, S. (2020). Analysis of ordered composite endpoints. Statistics in Medicine, 39(5), 602-616.