brca {nspmix}

Z-values of BRCA Data

Description

Contains 3226 z-values computed by Efron (2004) from the data obtained in a well-known microarray experiment concerning two types of genetic mutations causing increased breast cancer risk, BRCA1 and BRCA2.

Format

A numeric vector containing 3226 z-values.

References

Efron, B. (2004). Large-scale simultaneous hypothesis testing: the choice of a null hypothesis. Journal of the American Statistical Association, 99, 96-104.

Wang, Y. (2007). On fast computation of the non-parametric maximum likelihood estimate of a mixing distribution. Journal of the Royal Statistical Society, Ser. B, 69, 185-198.

Wang, Y. and C.-S. Chee (2012). Density estimation using nonparametric and semiparametric mixtures. Statistical Modelling: An International Journal, 12, 67-92.

See Also

npnorm,cnm.

Examples

data(brca)
x = npnorm(brca)
plot(cnm(x), x)