vpcCensTad {nlmixr2}

VPC based on ui model

Description

VPC based on ui model

Usage

vpcCensTad(..., cens = TRUE, idv = "tad")

Arguments

...

Additional arguments passed to nlmixr2plot::vpcCensTad().

cens

is a boolean to show if this is a censoring plot or not. When cens=TRUE this is actually a censoring vpc plot (with vpcCens() and vpcCensTad()). When cens=FALSE this is traditional VPC plot (vpcPlot() and vpcPlotTad()).

idv

Name of independent variable. For vpcPlot() and vpcCens() the default is "time" for vpcPlotTad() and vpcCensTad() this is "tad"

Value

Simulated dataset (invisibly)

Author(s)

Matthew L. Fidler

Examples

one.cmt <- function() {
 ini({
   tka <- 0.45; label("Ka")
   tcl <- log(c(0, 2.7, 100)); label("Cl")
   tv <- 3.45; label("V")
   eta.ka ~ 0.6
   eta.cl ~ 0.3
   eta.v ~ 0.1
   add.sd <- 0.7; label("Additive residual error")
 })
 model({
   ka <- exp(tka + eta.ka)
   cl <- exp(tcl + eta.cl)
   v <- exp(tv + eta.v)
   linCmt() ~ add(add.sd)
 })
}

fit <-
  nlmixr2est::nlmixr(
    one.cmt,
    data = nlmixr2data::theo_sd,
    est = "saem",
    control = list(print = 0)
  )

vpcPlot(fit)