Dialyzer {nlme}

High-Flux Hemodialyzer

Description

The Dialyzer data frame has 140 rows and 5 columns.

Format

This data frame contains the following columns:

Subject

an ordered factor with levels 10 < 8 < 2 < 6 < 3 < 5 < 9 < 7 < 1 < 4 < 17 < 20 < 11 < 12 < 16 < 13 < 14 < 18 < 15 < 19 giving the unique identifier for each subject

QB

a factor with levels 200 and 300 giving the bovine blood flow rate (dL/min).

pressure

a numeric vector giving the transmembrane pressure (dmHg).

rate

the hemodialyzer ultrafiltration rate (mL/hr).

index

index of observation within subject—1 through 7.

Details

Vonesh and Carter (1992) describe data measured on high-flux hemodialyzers to assess their in vivo ultrafiltration characteristics. The ultrafiltration rates (in mL/hr) of 20 high-flux dialyzers were measured at seven different transmembrane pressures (in dmHg). The in vitro evaluation of the dialyzers used bovine blood at flow rates of either 200~dl/min or 300~dl/min. The data, are also analyzed in Littell, Milliken, Stroup, and Wolfinger (1996).

Source

Pinheiro, J. C. and Bates, D. M. (2000), Mixed-Effects Models in S and S-PLUS, Springer, New York. (Appendix A.6)

Vonesh, E. F. and Carter, R. L. (1992), Mixed-effects nonlinear regression for unbalanced repeated measures, Biometrics, 48, 1-18.

Littell, R. C., Milliken, G. A., Stroup, W. W. and Wolfinger, R. D. (1996), SAS System for Mixed Models, SAS Institute, Cary, NC.