NCA Calculations and Population Model Diagnosis

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Documentation for package ‘ncappc’ version 0.3.0

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

calc.stat	Calculates a set of statistics for a given array of numbers.
dv.plot	Plots drug plasma concentration vs time data
est.nca	Estimate individual NCA metrics.
histobs.plot	Plots histogram of selected set of NCA metrics.
histpop.plot	Plots population histogram of the NCA metrics selected for model diagnosis.
nca.check.obs	Check observed data
nca.check.sim	Check simulated data
nca.deviation.plot	Plot individual deviation of NCA metrics estimated from observed and simulated data
nca.ind.data	Prepare individual PK data
nca.npde	Calculates individual normalized prediction distribution errors (NPDE) from PDE data.
nca.npde.plot	Plots population histogram of the NCA metrics selected for model diagnosis.
nca.pde.deviation.outlier	Calculates individual prediction distribution errors (PDE) and scaled deviation of NCA metrics estimated from observed and simulated data. Identifies outlier to population PK model.
nca.read.sim	Check observed data
ncappc	Performs NCA calculations and population PK model diagnosis.
nca_ind_data	Prepare individual PK data
out.digits	output value with correct digits and trailing zero
read_nm_table	Read NONMEM table files produced.