getCosmicSignatures {mutSignatures}

Obtain COSMIC mutational Signatures.

Description

Obtain latest mutational Signature definitions from COSMIC. FOr more info, please visit: https://cancer.sanger.ac.uk/cosmic/

Usage

getCosmicSignatures(forceUseMirror = FALSE, asMutSign = TRUE)

Arguments

forceUseMirror

logical, shall signatures be downloaded from a mirror. Set to TRUE if the COSMIC server goes down.

asMutSign

logical, shall data be returned as a mutSignatures-class object. Defaults to TRUE

Details

This function is part of the user-interface set of tools included in mutSignatures. This is an exported function.

Value

an object storing COSMIC mutational signature data

Author(s)

Damiano Fantini, [e-mail]

References

More information and examples about mutational signature analysis can be found here:

1. GitHub Repo: https://github.com/dami82/mutSignatures/

2. More info and examples about the mutSignatures R library: https://www.data-pulse.com/dev_site/mutsignatures/

3. Sci Rep paper, introducing mutS: https://www.nature.com/articles/s41598-020-75062-0/

4. Oncogene paper, Mutational Signatures Operative in Bladder Cancer: https://www.nature.com/articles/s41388-017-0099-6