| dodata {mrbayes} | R Documentation |
Dataset from Do et al., Nat Gen, 2013 containing summary level data on associations of genotypes with lipid traits and the risk of coronary heart diseases
Description
A summary-level dataset, from Do et al. (2013) doi: 10.1038/ng.2795, containing 185 single nucleodtide polymorphisms (SNPs) which have genotype-phenotype associations and standard errors for LDL-C, HDL-C, Triglycerides, and genotype-outcome associations for coronary heart disease with their respective standard errors.
Usage
dodata
Format
A data frame with 185 rows and 21 columns with the following variables:
- rsid
RSID number
- a1
Allele 1
- a2
Allele 2
- chr
Chromosome
- pos
Genomic position
- ldlcbeta
The genotype-low-density lipoprotein cholestrol associations
- hdlcbeta
The genotype-high-density lipoprotein cholestrol associations
- tgbeta
The genotype-triglyceride associations
- chdbeta
The genotype-coronary heart disease associations, on the log odds ratio scale
- ldlcp2
P-value for genotype-LDL-C associations
- hdlcp2
P-value for genotype-HDL-C associations
- tgp2
P-value for genotype-triglyceride associations
- chdp2
P-value for genotype-coronary heart disease associations
- ldlcz
Z-score for genotype-LDL-C associations
- ldlcse
The standard errors of the genotype-low-density lipoprotein cholestrol associations
- hdlcz
Z-score for genotype-HDL-C associations
- hdlcse
The standard errors of the genotype-high-density lipoprotein cholestrol associations
- tgz
Z-score for genotype-triglyceride associations
- tgse
The standard errors of the genotype-triglyceride cholestrol associations
- chdz
Z-score for genotype-coronary heart disease associations
- chdse
The standard errors of the genotype-coronary heart disease associations
Details
dodata.
References
Do, R. et al., Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics, 2013, 45, 1345-1352, doi: 10.1038/ng.2795.