nelsonaalen {mice} | R Documentation |
Cumulative hazard rate or Nelson-Aalen estimator
Description
Calculates the cumulative hazard rate (Nelson-Aalen estimator)
Usage
nelsonaalen(data, timevar, statusvar)
Arguments
data |
A data frame containing the data. |
timevar |
The name of the time variable in |
statusvar |
The name of the event variable, e.g. death in |
Details
This function is useful for imputing variables that depend on survival time. White and Royston (2009) suggested using the cumulative hazard to the survival time H0(T) rather than T or log(T) as a predictor in imputation models. See section 7.1 of Van Buuren (2012) for an example.
Value
A vector with nrow(data)
elements containing the Nelson-Aalen
estimates of the cumulative hazard function.
Author(s)
Stef van Buuren, 2012
References
White, I. R., Royston, P. (2009). Imputing missing covariate values for the Cox model. Statistics in Medicine, 28(15), 1982-1998.
Van Buuren, S. (2018). Flexible Imputation of Missing Data. Second Edition. Chapman & Hall/CRC. Boca Raton, FL.
Examples
require(MASS)
leuk$status <- 1 ## no censoring occurs in leuk data (MASS)
ch <- nelsonaalen(leuk, time, status)
plot(x = leuk$time, y = ch, ylab = "Cumulative hazard", xlab = "Time")
### See example on http://www.engineeredsoftware.com/lmar/pe_cum_hazard_function.htm
time <- c(43, 67, 92, 94, 149, rep(149, 7))
status <- c(rep(1, 5), rep(0, 7))
eng <- data.frame(time, status)
ch <- nelsonaalen(eng, time, status)
plot(x = time, y = ch, ylab = "Cumulative hazard", xlab = "Time")