sodium {mecor}

TONE sodium data [outcome-calibration study]

Description

Self-reported sodium intake and urinary sodium in the TONE study, a randomized controlled trial designed to investigate whether a reduction in sodium intake results in satisfactory blood pressure control. Two replicate urinary sodium measures were available in 50% of the subjects included in the trial.

Usage

sodium

Format

A data frame with 1000 rows and 4 variables:

recall

Sodium intake measured by a 24h recall (mg)

diet

Usual diet or sodium-lowering diet (0 = usual, 1 = sodium-lowering)

urinary1

Sodium intake measured in urine (1st measure, mg)

urinary2

Sodium intake measured in urine (2nd measure, mg)

Details

This is a simulated data set inspired by the TONE study <doi: 10.1016/1047-2797(94)00056-y>. A motivating example using the example data can be found here: <doi:10.1002/sim.7011>

References

Lawrence J Appel, Mark Espeland, Paul K Whelton, Therese Dolecek, Shiriki Kumanyika, William B Applegate, Walter H Ettinger, John B Kostis, Alan C Wilson, Clifton Lacy, and Stephen T Miller. Trial of Nonpharmacologic Intervention in the Elderly (TONE). Design and rationale of a blood pressure control trial. Annals of Epidemiology (1995). <doi: 10.1016/1047-2797(94)00056-y>

Ruth H Keogh, Raymond J Carroll, Janet A Tooze, Sharon I Kirkpatrick, Laurence S Freedman. Statistical issues related to dietary intake as the response variable in intervention trials. Statistics in Medicine (2016). <doi:10.1002/sim.7011>

Examples

data("sodium", package = "mecor")