haemoglobin {mecor}R Documentation

Low-dose iron supplements haemoglobin data [internal outcome-validation study]

Description

Capillary haemoglobin and venous haemoglobin levels of 400 subjects of a trial investigating the efficacy of low-dose iron supplements during pregnancy. Venous haemoglobin levels were observed of approximately 25% of the subjects included in the trial.

Usage

haemoglobin

Format

A data frame with 400 rows and 3 variables:

capillary

Haemoglobin levels measured in capillary blood (g/L)

supplement

Low-dose iron supplement (20 mg/d) (0 = no, 1 = yes)

venous

Haemoglobin levels measured in venous blood (g/L)

Details

This is a simulated data set inspired by a trial investigating low-dose iron supplements <doi:10.1093/ajcn/78.1.145>. A motivating example using the example data can be found here: <doi:10.1002/sim.8359>

References

Maria Makrides, Caroline A Crowther, Robert A Gibson, Rosalind S Gibson, and C Murray Skeaff. Efficacy and tolerability of low-dose iron supplements during pregnancy: a randomized controlled trial. The American Journal of Clinical Nutrition (2003). <doi:10.1093/ajcn/78.1.145>

Linda Nab, Rolf HH Groenwold, Paco MJ Welsing, and Maarten van Smeden. Measurement error in continuous endpoints in randomised trials: Problems and solutions. Statistics in Medicine (2019). <doi:10.1002/sim.8359>

Examples

data("haemoglobin", package = "mecor")

[Package mecor version 1.0.0 Index]