ActCosinor2 {mMARCH.AC}

Cosinor Model for Circadian Rhythmicity

Description

A parametric approach to study circadian rhythmicity assuming cosinor shape.

Usage

ActCosinor2(x, window = 1, n1440 = 1440)

Arguments

x

vector vector of dimension n*1440 which reprsents n days of 1440 minute activity data

window

The calculation needs the window size of the data. E.g window = 1 means each epoch is in one-minute window.

n1440

the number of points of a day. Default is 1440 for the minute-level data.

Value

A list with elements

mes

MESOR which is short for midline statistics of rhythm, which is a rhythm adjusted mean. This represents mean activity level.

amp

amplitude, a measure of half the extend of predictable variation within a cycle. This represents the highest activity one can achieve.

acro

acrophase, a meaure of the time of the overall high values recurring in each cycle. Here it has a unit of radian. This represents time to reach the peak.

acrotime

acrophase in the unit of the time (hours)

ndays

Number of days modeled

References

Cornelissen, G. Cosinor-based rhythmometry. Theor Biol Med Model 11, 16 (2014). https://doi.org/10.1186/1742-4682-11-16