| kmdiff {lrstat} | R Documentation |
Estimate of milestone survival difference
Description
Obtains the estimate of milestone survival difference between two treatment groups.
Usage
kmdiff(
data,
rep = "rep",
stratum = "stratum",
treat = "treat",
time = "time",
event = "event",
milestone = NA_real_,
survDiffH0 = 0,
confint = 0.95
)
Arguments
data |
The input data frame that contains the following variables:
|
rep |
The name of the replication variable in the input data. |
stratum |
The name of the stratum variable in the input data. |
treat |
The name of the treatment variable in the input data. |
time |
The name of the time variable in the input data. |
event |
The name of the event variable in the input data. |
milestone |
The milestone time at which to calculate the survival probability. |
survDiffH0 |
The difference in milestone survival probabilities under the null hypothesis. Defaults to 0 for superiority test. |
confint |
The level of the two-sided confidence interval for the difference in milestone survival probabilities. Defaults to 0.95. |
Value
A data frame with the following variables:
-
rep: The replication. -
milestone: The milestone time relative to randomization. -
survDiffH0: The difference in milestone survival probabilities under the null hypothesis. -
surv1: The estimated milestone survival probability for the treatment group. -
surv2: The estimated milestone survival probability for the control group. -
survDiff: The estimated difference in milestone survival probabilities. -
vsurv1: The variance for surv1. -
vsurv2: The variance for surv2. -
vsurvDiff: The variance for survDiff. -
survDiffZ: The Z-statistic value. -
survDiffPValue: The one-sided p-value. -
lower: The lower bound of confidence interval. -
upper: The upper bound of confidence interval. -
confint: The level of confidence interval.
Author(s)
Kaifeng Lu, kaifenglu@gmail.com
Examples
df <- kmdiff(data = rawdata, rep = "iterationNumber",
stratum = "stratum", treat = "treatmentGroup",
time = "timeUnderObservation", event = "event",
milestone = 12)
head(df)