logisticRR {logisticRR}

Calculate adjusted relative risks

Description

When response variable is binary and exposure variable is binary or continuous, this function derives adjusted relative risks conditional on fixed other confounders' value from logistic regression.

Usage

logisticRR(
  formula,
  basecov = 0,
  fixcov = NULL,
  data,
  boot = FALSE,
  n.boot = 100
)

Arguments

formula

a formula term that is passed into glm() having a form of response ~ terms where response is binary response vector and terms is a collection of terms connected by '+'. The first term of predictors will be used as a predictor of interest to calculate relative risks with respect to response variable.

basecov

a baseline value of exposure variable. Defaults to 0.

fixcov

a data frame of fixed value for each of adjusted confounders. If there is no confounder other than an exposure variable of interest, fixcov = NULL; if fixcov is missing for covariates, they are all set to 0 (for numerical covariates) or first levels (for factor covariates).

data

a data frame containing response variable and all the terms used in formula.

boot

a logical value whether bootstrap samples are generated or not. Defaults to FALSE.

n.boot

if boot = TRUE, the number of bootstrap samples. Defaults to 100.

Value

fit

an object of class glm.

RR

(conditional) relative risk in response under exposure at baseline (basecov) and basecov + 1.

delta.var

estimated variance of relative risk (RR) using Delta method.

boot.rr

if boot = TRUE, a vector of RR's using bootstrap samples.

boot.var

estimated sampled variance using bootstraps if boot = TRUE.

fix.cov

a data frame of fixed value for each of adjsuted confounders.

Author(s)

Youjin Lee

Examples

n <- 500
set.seed(1234)
X <- rbinom(n, 1, 0.3)
W <- rbinom(n, 1, 0.3);
W[sample(1:n, n/3)] = 2
Y <- rbinom(n, 1, plogis(X - W))
dat <- as.data.frame(cbind(Y, X, W))
result <- logisticRR(Y ~ X + W, basecov = 0, data = dat,
                    boot = TRUE, n.boot = 200)