| p.adj.perm {kyotil} | R Documentation |
Permutation-based Multitesting P Values Adjustment
Description
An implementation of Westfall and Young
Usage
p.adj.perm(p.unadj, p.perms, alpha = 0.05)
Arguments
p.unadj |
p.unadj |
p.perms |
p.perms |
alpha |
alpha |
Details
This implementation is not as fast as the implementation from the package multtest. But ususally the step to create p.perms is the rate-limiting step.
The smallest of the Westfall and Young FWER-controlling multitesting adjusted p values coincides with the p value for testing a global null without any assumptions. But for the multitesting adjustment to hold, it requires the subset pivotality condition.
Author(s)
Sue Li, sli@fredhutch.org
References
Westfall, P. H., & Young, S. S. (1993). Resampling-based multiple testing: Examples and methods for p-value adjustment (Vol. 279). John Wiley & Sons.
Westfall, P. H., & Troendle, J. F. (2008). Multiple testing with minimal assumptions. Biometrical Journal: Journal of Mathematical Methods in Biosciences, 50(5), 745-755.