| stemcells {jarbes} | R Documentation |
Meta-analysis of 31 randomized controled trials (RCTs) with reported discrepancies
Description
Meta-analysis of 31 randomized controled trials (RCTs) of two treatment groups of heart disease patients, where the treatment group received bone marrow stem cells and the control group a placebo treatment.
Format
A matrix with 31 rows and 5 columns. Each row represents study results, the columns are:
- trial
ID name of the trial.
- effect.size
treatment effect is measured as the difference of the ejection fraction between groups, which measures the improvement of left ventricular function in the heart.
- se.effect
Standard Error of the effect.size.
- sample.size
Total number of patients in the trial.
- n.discrep
Number of detected discrepancies in the published trial. Discrepancies are defined as two or more reported facts that cannot both be true because they are logically or mathematically incompatible.
Source
Nowbar, A N, et al. (2014) Discrepancies in autologous bone marrow stem cell trials and enhancemen of ejection fraction (DAMASCENE): weighted regression and meta-analysis. BMJ, 348,1-9.
References
Verde, P. E. (2017) Two Examples of Bayesian Evidence Synthesis with the Hierarchical Meta-Regression Approach. Chap.9, pag 189-206. Bayesian Inference, ed. Tejedor, Javier Prieto. InTech.