DLBCL {ipred}

Diffuse Large B-Cell Lymphoma

Description

A data frame with gene expression data from diffuse large B-cell lymphoma (DLBCL) patients.

Usage

data("DLBCL")

Format

This data frame contains the following columns:

DLCL.Sample

DLBCL identifier.

Gene.Expression

Gene expression group.

time

survival time in month.

cens

censoring: 0 censored, 1 dead.

IPI

International prognostic index.

MGEc.1

mean gene expression in cluster 1.

MGEc.2

mean gene expression in cluster 2.

MGEc.3

mean gene expression in cluster 3.

MGEc.4

mean gene expression in cluster 4.

MGEc.5

mean gene expression in cluster 5.

MGEc.6

mean gene expression in cluster 6.

MGEc.7

mean gene expression in cluster 7.

MGEc.8

mean gene expression in cluster 8.

MGEc.9

mean gene expression in cluster 9.

MGEc.10

mean gene expression in cluster 10.

Source

Except of MGE, the data is published at http://llmpp.nih.gov/lymphoma/data.shtml. MGEc.* is the mean of the gene expression in each of ten clusters derived by agglomerative average linkage hierarchical cluster analysis (Hothorn et al., 2002).

References

Ash A. Alizadeh et. al (2000), Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature, 403, 504–509.

Torsten Hothorn, Berthold Lausen, Axel Benner and Martin Radespiel-Troeger (2004), Bagging Survival Trees. Statistics in Medicine, 23, 77–91.

Examples

suppressWarnings(RNGversion("3.5.3"))
set.seed(290875)

data("DLBCL", package="ipred")
library("survival")
survfit(Surv(time, cens) ~ 1, data=DLBCL)