breastCancer {icensBKL}

Cosmetic Data on Breast Cancer Patients

Description

Breadle et al. (1984a, 1984b) report a retrospective study carried out to compare the cosmetic effects of radiotherapy alone versus radiotherapy and adjuvant chemotherapy on women with early breast cancer.

Patients were observed initially every 4 to 6 months, but as their recovery progressed, the interval betwenn visits lengthened. At each visit, the clinician recorded a measure of breast retraction on a 3-point scale (none, moderate, severe). Event of interest was the time to first appearance of moderate or severe breast retraction.

The subjects in this data were patients who had been treated at the Joint Center for Radiation Therapy in Boston between 1976 and 1980.

Usage

data(breastCancer)

Format

a data frame with 94 rows and the following variables

low

lower limit of interval (lower,upper] that contains the event of interest (months). It is NA for left-censored observations.

upp

upper limit of interval (lower,upper] that contains the event of interest (months). It is NA for right-censored observations.

treat

treatment regimen

1 = radio only =

radiotherapy only

2 = radio+chemo =

radiotherapy + chemotherapy

Source

Finkelstein, D. M. and Wolfe, R. A. (1985). A semiparametric model for regression analysis of interval-censored failure time data. Biometrics, 41, 933-945. Table 4.

References

Beadle, G. F., Harris, J. R., Silver, B., Botnick, L., and Hellman, S. (1984a). Cosmetic results following primary radiation therapy for early breast cancer. Cancer, 54, 2911-2918.

Beadle, G. F., Harris, J. R., Come, S., Henderson, C., Silver, B., and Hellman, S. (1984b). The effect of adjuvant chemotherapy on the cosmetic results after primary radiation treatment for early stage breast cancer: A preliminary analysis. International Journal of Radiation Oncology, Biology and Physics, 10, 2131-2137.

Examples

data("breastCancer", package="icensBKL")
summary(breastCancer)