| actg036 {hdbayes} | R Documentation |
AIDS Clinical Trial ACTG036
Description
A data set from the AIDS clinical trial ACTG036 (https://clinicaltrials.gov/study/NCT00001104) comparing zidovudine (AZT) with a placebo in patients with hereditary coagulation disorders and HIV infection. The study results were described in Merigan et al. (1991) doi:10.1182/blood.V78.4.900.900. This data set has the same variables as the actg019 data set. We can use the actg019 data as the historical data and the actg036 data as the current data.
Usage
actg036
Format
A data frame with 183 rows and 5 variables:
- outcome
outcome variable with 1 indicating death, development of AIDS or AIDS-related complex (ARC) and 0 otherwise
- age
patient age in years
- treatment
treatment indicator, 0 = placebo, 1 = AZT
- race
race indicator, 0 = non-white, 1 = white
- cd4
CD4 cell count
References
Merigan, T., Amato, D., Balsley, J., Power, M., Price, W., Benoit, S., Perez-Michael, A., Brownstein, A., Kramer, A., and Brettler, D. (1991). Placebo-controlled trial to evaluate zidovudine in treatment of human immunodeficiency virus infection in asymptomatic patients with hemophilia. NHF-ACTG 036 Study Group. Blood, 78(4), 900–906.
Chen, M.-H., Ibrahim, J. G., and Yiannoutsos, C. (1999). Prior elicitation, Variable Selection and Bayesian computation for Logistic Regression Models. Journal of the Royal Statistical Society Series B: Statistical Methodology, 61(1), 223–242.