actg019 {hdbayes}R Documentation

AIDS Clinical Trial ACTG019

Description

A data set from the AIDS clinical trial ACTG019 (https://clinicaltrials.gov/ct2/show/NCT00000736) comparing zidovudine (AZT) with a placebo in adults with asymptomatic HIV infection. The study results were described in Volberding et al. (1990) doi:10.1056/NEJM199004053221401.

Usage

actg019

Format

A data frame with 822 rows and 5 variables:

outcome

outcome variable with 1 indicating death, development of AIDS or AIDS-related complex (ARC) and 0 otherwise

age

patient age in years

treatment

treatment indicator, 0 = placebo, 1 = AZT

race

race indicator, 0 = non-white, 1 = white

cd4

CD4 cell count

References

Volberding, P. A., Lagakos, S. W., Koch, M. A., Pettinelli, C., Myers, M. W., Booth, D. K., Balfour, H. H., Reichman, R. C., Bartlett, J. A., Hirsch, M. S., Murphy, R. L., Hardy, W. D., Soeiro, R., Fischl, M. A., Bartlett, J. G., Merigan, T. C., Hyslop, N. E., Richman, D. D., Valentine, F. T., Corey, L., and the AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases (1990). Zidovudine in asymptomatic human immunodeficiency virus infection. New England Journal of Medicine, 322(14), 941–949.

Chen, M.-H., Ibrahim, J. G., and Yiannoutsos, C. (1999). Prior elicitation, Variable Selection and Bayesian computation for Logistic Regression Models. Journal of the Royal Statistical Society Series B: Statistical Methodology, 61(1), 223–242.


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