hbim-package {hbim}

Hill/Bliss Independence Model for Multicomponent Vaccines

Description

Calculate expected relative risk and proportion protected assuming normally distributed log10 transformed antibody dose for several component vaccine. Uses Hill models for each component which are combined under Bliss independence. (see Saul and Fay (2007) <doi:10.1371/jounal.pone.0000850>).

Details

The hbim package allows users to reproduce plots and calculations for Saul and Fay (2007). See vignette("hbimdetails").

Author(s)

M.P. Fay, Maintainer: Michael Fay <[e-mail]>

References

Saul A, Fay MP (2007). Human Immunity and the Design of Multi-Component, Single Target Vaccines. PLoS ONE 2(9): e850. doi:10.1371/jounal.pone.0000850