PvalueFam {groupedSurv}

Estimate P-values of the Efficient Score Statistics for the Frailty Model

Description

A method to estimate the p-value for the efficient score statistics for the frailty model.

Usage

  PvalueFam(U)  	

Arguments

U

Matrix of contributions of each family to the efficient score statistics of each variable of interest, (i.e., the output from groupedSurvFam).

Value

A data.frame with one row for each variables of interest and four columns: stat, the efficient score statistic, pvalue, unadjusted p-value, FWER, the family-wise error rate adjusted p-value (Bonferroni correction), and FDR, the local false-discovery rate (Storey's Q-value).

References

Bonferroni, C.E. (1935). Il calcolo delle assicurazioni su gruppi di teste. Studi in Onore del Professore Salvatore Ortu Carbon, 13-60.
Storey, J.D. (2003). The positive false discovery rate: a Bayesian interpretation and the q-value. Annals of Statistics, 31:6, 2013-2035.
Storey, J.D., Taylor, J.E., and Siegmund, D. (2004). Strong control, conservative point estimation and simultaneous conservative consistency of false discovery rates: a unified approach. Journal of the Royal Statistical Society Series B-Statistical Methodology, 66, 187-205

Examples

# Generate dummy data	
U <- matrix(rnorm(10000), ncol=50)

#res   <- PvalueFam(U) 
#res