Generalised Survival Trial Assessment Tool Environment


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Documentation for package ‘gestate’ version 1.6.0

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analyse_sim Analyse simulations of time-to-event data using arbitrary event, censoring and recruitment distributions.
Blank Blank Curve constructor function
createRFfunction Method for creating a random draw function from a Curve object
createRFfunction-method Method for creating a random draw function from a Curve object
create_tte_prior Create an arbitrary prior data set from a specified Curve object
Curve-class Curve Class for defining distributions
evaluateCDFfunction Method for evaluating the CDF function for a Curve object at q
evaluateCDFfunction-method Method for evaluating the CDF function for a Curve object at q
evaluateInvfunction Method for evaluating the inverse-CDF function for a Curve object at p
evaluateInvfunction-method Method for evaluating the inverse-CDF function for a Curve object at p
evaluatePDFfunction Method for evaluating the PDF function for a Curve object at x
evaluatePDFfunction-method Method for evaluating the PDF function for a Curve object at x
event_prediction Event prediction using patient-level survival data and a recruitment RCurve
event_prediction_KM Event prediction using a lifetable and a recruitment RCurve
event_prediction_prior Event prediction using patient-level survival data, prior data and a recruitment RCurve
Exponential Exponential Curve constructor function
fit_KM Fit Weibull, Log-Normal or Exponential survival curves to Kaplan Meier estimates
fit_tte_data Fit Weibull, Log-Normal or Exponential survival curves to patient-level time-to-event data
fit_tte_data_prior Fit Weibull survival curves to patient-level time-to-event data by including patient-level weighted prior data
frontierpower Calculate Frontier power from number of events
getAssessCDFfunction Method for returning the CDF function for a RCurve object
getAssessCDFfunction-method Method for returning the CDF function for a RCurve object
getCDFfunction Method for returning the CDF function for a Curve object
getCDFfunction-method Method for returning the CDF function for a Curve object
getInvfunction Method for returning the inverse-CDF function for a Curve object
getInvfunction-method Method for returning the inverse-CDF function for a Curve object
getLength Method for returning the recruitment length from a RCurve
getLength-method Method for returning the recruitment length from a RCurve
getMaxF Method for returning maximum duration of patient follow-up from a RCurve
getMaxF-method Method for returning maximum duration of patient follow-up from a RCurve
getN Method for returning the total patient number from a RCurve
getN-method Method for returning the total patient number from a RCurve
getNactive Method for returning the active arm patient number from a RCurve
getNactive-method Method for returning the active arm patient number from a RCurve
getNames Method for returning all parameter names from a Curve object
getNames-method Method for returning all parameter names from a Curve object
getNcontrol Method for returning the control arm patient number from a RCurve
getNcontrol-method Method for returning the control arm patient number from a RCurve
getParam Method for returning a single parameter from a Curve object
getParam-method Method for returning a single parameter from a Curve object
getParams Method for returning all parameters from a Curve object as a list
getParams-method Method for returning all parameters from a Curve object as a list
getParamsV Method for returning all parameters from a Curve object as a vector
getParamsV-method Method for returning all parameters from a Curve object as a vector
getPatients Method for calculating expected number of recruited patients at a given time from an RCurve
getPatients-method Method for calculating expected number of recruited patients at a given time from an RCurve
getPDFfunction Method for returning the PDF function for a Curve object
getPDFfunction-method Method for returning the PDF function for a Curve object
getRatio Method for returning the recruitment ratio from a RCurve
getRatio-method Method for returning the recruitment ratio from a RCurve
getRFfunction Method for returning the RF function for a Curve object
getRFfunction-method Method for returning the RF function for a Curve object
getType Method for returning the Curve type
getType-method Method for returning the Curve type
GGamma Generalised Gamma Curve constructor function
Gompertz Gompertz Curve constructor function
InstantR InstantR RCurve constructor function
LinearR LinearR RCurve constructor function
LogLogistic Log-logistic Curve constructor function
Lognormal Log-normal Curve constructor function
MixExp Mixture Exponential Curve constructor function
MixWei Mixture Weibull Curve constructor function
nph_traj Calculate analytic time-to-event trial properties under non-proportional hazards and complex assumptions
PieceExponential Piecewise Exponential Curve constructor function
PieceR PieceR RCurve constructor function
PieceRMaxF PieceR RCurve constructor function
plotCDF Method for plotting the CDF of a Curve object
plotCDF-method Method for plotting the CDF of a Curve object
plotRecruitment Method for plotting the Recruitment Function of a RCurve object
plotRecruitment-method Method for plotting the Recruitment Function of a RCurve object
plotSF Method for plotting the Survival Function of a Curve object
plotSF-method Method for plotting the Survival Function of a Curve object
plot_ep Plot event prediction output
plot_km_fit Kaplan Meier Plot of Curve-Fit
plot_npht Plot output from nph_traj
random_draw Method for taking random draws from a Curve object distribution
random_draw-method Method for taking random draws from a Curve object distribution
RCurve-class RCurve Class for defining recruitment distributions
run_gestate Load Shiny for Gestate Loads the Shiny interactive GUI for gestate
setPatients Method for setting N's in an RCurve
setPatients-method Method for setting N's in an RCurve
set_assess_time Adjusts assessment time for simulations
set_event_number Adjusts simulations so that administrative censoring occurs at a fixed event number, rather than a fixed time
show-method Method for displaying Curve objects neatly - replaces standard show method
show-method Method for displaying RCurve objects neatly - replaces standard show method
simulate_trials Perform simulations of time-to-event data using arbitrary event, censoring and recruitment distributions.
simulate_trials_strata Perform multi-strata simulations of time-to-event data using arbitrary event, censoring and recruitment distributions.
summarise_analysis Summarise analyses of simulations of time-to-event data using arbitrary event, censoring and recruitment distributions.
survfit_fast Create lifetable quickly
Weibull Weibull Curve constructor function