alteplase {genodds}

Effect of time to treatment on efficacy of rt-PA in treating acute stroke

Description

A dataset reconstructing reported outcomes after stroke as reported in Lees et. al. (2010) which pooled the results of several studies.

Usage

alteplase

Format

A data frame with 3669 rows and 3 variables:

time

Time interval (minutes) between stroke onset and treatment

treat

Type of treatment received

mRS

Outcome at 3 months measured using the modified Rankin Scale

References

Lees, K. R., Bluhmki, E., Von Kummer, R., Brott, T. G., Toni, D., Grotta, J. C., Albers, G. W., Kaste, M., Marler, J. R., Hamilton, S. A., Tilley, B. C., Davis, S. M., Donnan, G. A., Hacke, W. (2010). Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. The Lancet, 375(9727), 1695-1703.