Estimates Allele Frequency on qPCR DeltaDeltaCq from Bulk Samples


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Documentation for package ‘freqpcr’ version 0.4.0

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.freqpcr_loglike Log-likelihood of obtaining Cq values under given parameter set.
.freqpcr_loglike_cont Log-likelihood when sample allele ratio is continuous.
CqFreq Output object of 'freqpcr()'.
CqFreq-class Output object of 'freqpcr()'.
CqList S4 class storing the dummy Cq data for performance test.
CqList-class S4 class storing the dummy Cq data for performance test.
freqpcr Estimate population allele frequency from the set of Cq measurements.
knownqpcr Estimate auxiliary parameters using samples with known allele ratios.
knownqpcr_unpaired Estimate auxiliary parameters when the sample pairs are incomplete.
make_dummy Generate dummy DNA dataset ready for allele-frequency estimation.
sim_dummy Simulate freqpcr estimation based on user-generated dummy data.