renal {frailtyHL}

Renal transplant data

Description

This is a data set from a clinical study to investigate the chronic renal allograft dysfunction in renal transplants (Ha et al., 2017). Data were available from 87 male and 25 female renal transplanted patients who survived more than 4 years after transplant. For each patient, both repeated-measure outcomes (serum creatinine levels) at several time points and a terminating event time (graft-loss time) were observed.

Usage

data("renal")

Format

A data frame with 1395 observations on the following 9 variables.

id

Patient id

month

Time points (month) at which the measurements of sCr were recorded

cr

Serum creatinine (sCr) level

sex

Sex(1=male, 0=female)

age

Age(years)

icr

Reciprocal of sCr(=1/sCr)

sur_time

Time to graft loss

status

Censoring indicator(1=graft loss, 0=no event)

first

The first survival time (time to graft loss) of each patient

References

Ha, I. D., Noh, M. and Lee, Y. (2017). H-likelihood approach for joint modelling of longitudinal outcomes and time-to-event data. Biometrical Journal, 59, 1122–1143.

Ha, I. D., Jeong, J.-H. and Lee, Y. (2017). Statistical modelling of survival data with random effects: h-likelihood approach. Springer, in press.