bladder0 {frailtyHL}

Bladder cancer data

Description

Bladder0 is a subset of 410 patients from a full data set with bladder cancer from 21 centers that participated in the EORTC trial (Sylvester et al., 2006). Time to event is the duration of the disease free interval (DFI), which is defined as time from randomization to the date of the first recurrence.

Usage

data("bladder0")

Format

A data frame with 410 observations on the following 5 variables.

Center

Institution number of 24 centers

Surtime

Time to the first recurrence from randomization

Status

Censoring indicator(1=recurrence, 0=no event)

Chemo

Treatment indicator representing chemotherapy(0=No, 1=Yes)

Tustat

Indicator representing prior recurrent rate(0=Primary, 1=Recurrent)

References

Sylvester, R., van der Meijden, A.P.M., Oosterlinck, W., Witjes, J., Bouffioux, C., Denis, L., Newling, D.W.W. and Kurth, K. (2006). Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. European Urology, 49, 466-477.

Ha, I.D., Sylvester, R., Legrand, C. and MacKenzie, G. (2011). Frailty modelling for survival data from multi-centre clinical trials. Statistics in Medicine, 30, 28-37.