bladder {frailtyHL}

Bladder Cancer Data

Description

Bladder is an extension of Bladder0 to competing risks with 396 patients with bladder cancer from 21 centers, focusing on two competing endpoints, i.e, time to first bladder recurrence (an event of interest; Type 1 event) and time to death prior to recurrence (competing event; Type 2 event).

Usage

data("bladder")

Format

A data frame with 396 observations on the following 13 variables.

OBS

Observation number

center

Institution number of 24 centers

surtime

Time to event

status

Event indicator(1=recurrence, 2=death before recurrence, 0=no event)

CHEMO

Treatment indicator representing chemotherapy(0=No, 1=Yes)

AGE

Age(0, <= 65 years; 1, > 65 years)

SEX

Sex(0=male, 1=female)

PRIORREC

Prior recurrent rate(0, primary; 1, <= 1/yr; 2, > 1/yr)

NOTUM

Number of tumors(0, single; 1, 2-7 tumors; 2, >= 8 tumors)

TUM3CM

Tumor size(0, < 3cm; 1, >= cm)

TLOCC

T cotegory(0=Ta, 1=T1)

CIS

Carcinoma in situ (0=No, 1=Yes)

GLOCAL

G grage(0=G1, 1=G2, 2=G3)

References

Sylvester, R., van der Meijden, A.P.M., Oosterlinck, W., Witjes, J., Bouffioux, C., Denis, L., Newling, D.W.W. and Kurth, K. (2006). Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. European Urology, 49, 466-477.

Ha, I.D., Sylvester, R., Legrand, C. and MacKenzie, G. (2011). Frailty modelling for survival data from multi-centre clinical trials. Statistics in Medicine, 30, 28-37.