| flan-package {flan} | R Documentation |
Fluctuation analysis of mutant cell counts
Description
Statistical tools for fluctuation analysis of mutant cells counts.
Details
| Package: | flan |
| Type: | Package |
| Version: | 0.9 |
| Date: | 2021-05-26 |
| License: | GPL |
This package contains functions dedicated to :
- Distribution (dflan, pflan, qflan, and rflan): built as the classic distribution functions, like dnorm, pnorm, qnorm, and rnorm.
- Parametric estimation (mutestim): estimates of the parameters of interest, which are the mean number of mutations (or the mutation probability) and the fitness parameter.
- Parametric testing (flan.test): built as the classic test functions, like t.test.
Author(s)
Adrien Mazoyer, Rémy Drouilhet, Stéphane Despréaux, and Bernard Ycart
Maintainer: Adrien Mazoyer <adrien.mazoyer@math.univ-toulouse.fr>
References
A. Mazoyer: Fluctuation analysis on mutation models with birth-date dependence Math. Biosci. (2018)
A. Mazoyer: Time inhomogeneous mutation models with birth-date dependence B. Math. Biol. (2017)
A. Mazoyer, R. Drouilhet, S. Despréaux and B. Ycart: flan: An R Package for Inference on Mutation Models. R Journal 9(1) (2017)
B. Ycart and N. Veziris: Unbiased estimates of mutation rates under fluctuating final counts. PLoS one 9(7) e101434 (2014)
B. Ycart: Fluctuation analysis with cell deaths. J. Applied Probab. Statist, 9(1):12-28 (2014)
B. Ycart: Fluctuation analysis: can estimates be trusted? One PLoS one 8(12) e80958 (2013)
A. Hamon and B. Ycart: Statistics for the Luria-Delbrück distribution. Elect. J. Statist., 6:1251-1272 (2012)