fitPoly {fitPoly}

fitPoly: a package for assigning dosage scores based on SNP array data

Description

fitPoly (an evolved version of package fitTetra) fits mixture models to the distribution of intensity ratios Y/(X+Y) (where X and Y are the intensities of the signals produced by the A and B alleles of bi-allelic markers) and uses these to assign genotypes (dosages). The main differences compared with fitTetra are that it can handle any ploidy level, and multiple populations that can be either F1 populations (and their parents) or panels of accessions. There are also improvements in accuracy, speed and the possibility to use prior dosage information.