voomReads {fcros} | R Documentation |
Transformation of read count values
Description
This function allows to transform the count values associated with Sequencing reads. The purpose of this transformation is to allow applying normal-based microarray-like statistical methods to RNA-seq read counts. Log2 values are returned.
Usage
voomReads(x, Rm=1e+06)
Arguments
x |
This is a read counts matrix |
Rm |
A constant used in the transformation |
Value
This function returns a data matrix of the same size as input matrix x. The values of this matrix are expressed in log2 scale.
Author(s)
Doulaye Dembele doulaye@igbmc.fr
References
Charity W Law, Yunshun Chen, Wei Shi and Gordon K Smyth, voom: precision weights unlock linear model analysis tools for RNA-seq read counts,Genome Biology, 2014, 15R29
Examples
# data(fdata);
[Package fcros version 1.6.1 Index]