recrisk.ratio {fam.recrisk}

Recurrence risk ratio of familial recurrence risk

Description

Estimate the recurrence risk ratio of familial recurrence risk divided by population prevalence, based on results returned from fam.recrisk

Usage

recrisk.ratio(fit)

Arguments

fit

list returned from fam.recrisk

Details

The recurrence risk is based on a truncated binomial density, and the prevalence is the frequency of disease in the sample. If the sample of families in not a random sample from a population, the prevalence will be biased, and merely represent the frequency of disease in the sample.

Value

A list with the following values

rr

ratio of recurrence risk divided by population prevalence

var.rr

variance of rr

Author(s)

Schaid DJ, Sinnwell JP.

References

Schaid DJ, McDonnell SK, Thibodeau SN. Familial recurrence risk with varying amount of family history. Under review at Genetic Epidemiology, 2018.

Examples

  s <- c(4,  8,  6,  6,  10, 8,  7,  8,  5,  6,  10, 4,  4,  8,  6,  8,  4,  5,  9, 
         9,  5,  4,  4,  7,  3,  3,  9,  5,  3,  3,  4,  6,  8,  3,  5,  8,  6,  8, 9,  3)
  a <- c(3, 4, 2, 5, 4, 5, 3, 4, 3, 3, 8, 2, 0, 3, 4, 5, 2, 3, 4, 2, 1, 1,
         1, 1, 1, 0, 0, 0, 0, 0, 1, 0, 2, 0, 0, 1, 0, 2, 3, 0)
  fit <- fam.recrisk(s,a,1)
  recrisk.ratio(fit)