| leadworker {evident} | R Documentation | 
DNA Damage in Lead Workers
Description
Data from Table 1 of Wu et al. (2002) concerning DNA damage among lead workers compared to controls. In this example, the data have been matched for age and smoking, making 11 matched pairs. Used as an example in Rosenbaum (2021).
Usage
data("leadworker")Format
A data frame with 22 observations on the following 7 variables.
- mset
- Matched set indicator, 1, 2, ..., 11 
- group
- 1=lead worker, 0=control 
- age
- Age in years 
- smoking
- Smoking, pack-years 
- bll
- Blood lead level, mu-g/dl 
- dpc
- DNA-protein cross-links, percent 
- id
- ID number in the original study, before matching 
Details
The outcome, a measure of DNA damage is dpc.
Source
Fang-Yang Wu, Pao-Wen Chang, Chin-Ching Wu and Hsien-Wen Kuo (2002). "Correlations of Blood Lead with DNA-Protein Cross-Links and Sister Chromatid Exchanges in Lead Workers". Cancer Epidemiology, Biomarkers and Prevtion. March 1 2002 11 (3) 287-290.
References
Rosenbaum, Paul R. (2021) <doi:10.1201/9781003039648> Replication and Evidence Factors in Observational Studies. Chapman and Hall/CRC.
Examples
data(leadworker)
boxplot(leadworker$dpc~leadworker$group)