dip3 {disprofas}

Dissolution data of two different capsule formulations

Description

A data set containing the dissolution data of one reference batch and one test batch of n = 12 capsules each, i.e. the dissolution profiles of the % drug release observed at 15, 20 and 25 minutes.

Usage

data(dip3)

Format

A data frame with 24 observations and 6 variables:

cap

Factor with levels 1 to 12 representing individual capsules

batch

Factor with levels white and blue representing the colours of two different capsule formulations

type

Factor with levels ref (Reference) and test (Test)

x.15

Numeric of the % release at the 15 minutes testing point

x.20

Numeric of the % release at the 20 minutes testing point

x.25

Numeric of the % release at the 25 minutes testing point

Source

See reference: Example data set shown in Table 1. Data set ‘ex_data_JoBS’ from package ‘T2EQ’.

References

Hoffelder, T., Goessl, R., and Wellek, S. Multivariate equivalence tests for use in pharmaceutical development. J Biopharm Stat. 2015; 25(3): 417-437.
doi:10.1080/10543406.2014.920344

Examples

str(dip3)

if (requireNamespace("T2EQ")) {
library(T2EQ)

  data(ex_data_JoBS, envir = environment())
  str(ex_data_JoBS)
  rm(ex_data_JoBS)
}