dip2 {disprofas}

Dissolution data of one reference batch and five test batches

Description

A data set containing the dissolution data of one reference batch and five test batches of n = 12 tablets each, i.e. the dissolution profiles of the % drug release observed within a period of 180 minutes.

Usage

data(dip2)

Format

A data frame with 72 observations and 8 variables:

type

Factor with levels Reference and Test

tablet

Factor with levels 1 to 12 representing individual tablets

batch

Factor with levels b0, b1, b2, b3, b4 and b5

t.0

Numeric of the % release at the initial testing point

t.30

Numeric of the % release at the 30 minutes testing point

t.60

Numeric of the % release at the 60 minutes testing point

t.90

Numeric of the % release at the 90 minutes testing point

t.180

Numeric of the % release at the 180 minutes testing point

Source

See reference: Example data set shown in Table 4.

References

Shah, V. P., Tsong, Y., Sathe, P., and Liu, J. P. In vitro dissolution profile comparison - statistics and analysis of the similarity factor, f_2. Pharm Res. 1998; 15(6): 889-896.
doi:10.1023/A:1011976615750

Examples

str(dip2)