dfcomb-package {dfcomb} | R Documentation |
Phase I/II Adaptive Dose-Finding Design for Combination Studies
Description
Phase I/II adaptive dose-finding design for combination studies where toxicity rates are supposed to increase with both agents.
Details
The DESCRIPTION file:
Package: | dfcomb |
Type: | Package |
Title: | Phase I/II Adaptive Dose-Finding Design for Combination Studies |
Version: | 3.1-1 |
Date: | 2022-12-26 |
Author: | Marie-Karelle Riviere and Jacques-Henri Jourdan |
Maintainer: | Jacques-Henri Jourdan <jacques-henri.jourdan@normalesup.org> |
Copyright: | src/arms.c and src/arms.h are copyright Wally Gilks. All other files are copyright Sanofi-Aventis R&D, Institut de Recherches Internationales Servier and Institut national de la sante et de la recherche medicale. |
Description: | Phase I/II adaptive dose-finding design for combination studies where toxicity rates are supposed to increase with both agents. |
License: | GPL-3 |
Depends: | R (>= 3.2.3) |
LinkingTo: | BH (>= 1.55), Rcpp, RcppProgress (>= 0.2.1) |
NeedsCompilation: | yes |
Index of help topics:
CombIncrease_next Combination determination with logistic model CombIncrease_sim Combination design Simulator using Logistic model dfcomb-package Phase I/II Adaptive Dose-Finding Design for Combination Studies
Author(s)
Marie-Karelle Riviere and Jacques-Henri Jourdan
Maintainer: Jacques-Henri Jourdan <jacques-henri.jourdan@normalesup.org>
References
Riviere MK, Yuan Y, Dubois F, Zohar S (2014). A Bayesian dose-finding design for drug combination clinical trials based on the logistic model. Pharm Stat, 13, 4:247-57.
[Package dfcomb version 3.1-1 Index]