denvax {denvax}

denvax: Simple Dengue Test and Vaccinate Cost Thresholds

Description

Provides the mathematical model described by "Serostatus Testing & Dengue Vaccine Cost-Benefit Thresholds" in <doi:10.1098/rsif.2019.0234>. Using the functions in the package, that analysis can be repeated using sample life histories, either synthesized from local seroprevalence data using other functions in this package (as in the manuscript) or from some other source. The package provides a vignette which walks through the analysis in the publication, as well as a function to generate a project skeleton for such an analysis.

denvax functions

serofit

fits serosurvey data against two-risk model

synthetic.pop

using parameter fit data, generate a sample population

nPxA

estimate dengue infection outcome probabilities based on a synthetic population

ROIcoeffs

using population outcome probabilities, compute ROI equation coefficients

ROI

compute ROIs from setting coefficients and cost scenarios

build.project

create a template project for estimating ROIs