cci.pest {currentSurvival}R Documentation

Estimates Current Cumulative Incidence (CCI) Function

Description

This is an internal function and is not usually called by user.
This function estimates the current cumulative incidence (CCI), i.e. the probability that a patient is alive and in any disease remission after initiating his or her therapy.

Usage

cci.pest(E, LastContact, Exitus, maxx)

Arguments

E

a matrix with ascending times from therapy initiation to occurrence of individual events (in days); the size of the data matrix is n times (2*r), where n is the number of patients and r is the maximum number of disease remissions achieved by patients; the data matrix consists of the following columns:
E[,1] is the time from therapy initiation to achievement of the first disease remission
E[,2] is the time from therapy initiation to loss of the first disease remission
E[,3] is the time from therapy initiation to achievement of the second disease remission
...
E[,2*r-1] is the time from therapy initiation to achievement of the rth disease remission
E[,2*r] is the time from therapy initiation to loss of the rth disease remission

LastContact

a vector containing the follow-up time (time from therapy initiation to death or to the date of last contact with a patient)

Exitus

a vector containing the censoring indicators (1..patient died, 0..patient is censored)

maxx

maximum follow-up time in days

Value

x

days from 0 to maximum follow-up time maxx

y

CCI function estimates at each day

Author(s)

Eva Janousova, Tomas Pavlik
Institute of Biostatistics and Analyses
Masaryk University, Brno, Czech Republic
janousova@iba.muni.cz

References

Pavlik T., Janousova E., Pospisil Z., et al. (2011). Estimation of current cumulative incidence of leukaemia-free patients and current leukaemia-free survival in chronic myeloid leukaemia in the era of modern pharmacotherapy. BMC Med Res Methodol 11:140.

See Also

cci

Examples

# This is an internal function and is not usually called by user.

[Package currentSurvival version 1.1 Index]