match_seeds {crosstalkr}

Identify random sets of seeds with similar degree distribution to parent seed proteins

Description

This function will generate n character vectors of seeds to be passed to sparseRWR as part of the construction of a boostrapped null distribution for significance testing.

Usage

match_seeds(g, seed_proteins, n, set_seed = NULL)

Arguments

g

igraph object representing the network under study. specified by "ppi" in bootstrap_null

seed_proteins

user defined seed proteins

n

number of random walks with repeats to create null distribution

set_seed

integer to set random number seed - for reproducibility

Value

list of character vectors: randomly generated seed proteins with a similar degree distribution to parent seed proteins