crossdes-package {crossdes}

Design and Analysis of dose-finding studies

Description

The crossdes package provides functions for the construction of of carryover balanced crossover designs. In addition contains functions to check given designs for balance.

Details

Package:	crossdes
Type:	Package
Version:	1.1-1
Date:	2013-03-18
License:	GPL-2

The main functions are:
get.plan: Menu-driven selection of crossover designs
allcombs: Construct crossover design with all possible treatment orders
williams: Construct a Williams design
williams.BIB: Construct a crossover design based on a combination of balanced incomplete block designs and Williams designs.
des.MOLS: Construct crossover design based on mutually orthogonal Latin Squares
balmin.RMD: Construct balanced minimal repeated measurements crossover design
isCbalanced: Check whether a crossover design is balanced for first order carryover effects
isGYD: Check whether a crossover design is balanced

Author(s)

Martin Oliver Sailer

References

Earlier version of the package:
Sailer, O. (2005): crossdes: A package for design and randomization in crossover studies. Rnews 5/2, 24-27.

Overview on cross-over designs:
Jones, B. and Kenward, M.G. (1989): Design and Analysis of Cross-Over Trials. Chapman and Hall, London.

Wakeling, I.N. and MacFie, H.J.H. (1995): Designing consumer trials balanced for first and higher orders of carry-over effect when only a subset of k samples from t may be tested. Food Quality and Preference 6, 299-308.